Kim Camacho is a graduate of Harvard Business School, 1980 and an economics graduate, cum laude, from Radcliffe College, Harvard University, 1977. She trained in Seagrams Latin America in New York and worked for the National Development Company of the Philippines under the Minister of Trade and Industry. She then founded a fashion accessories business in 1984 before working briefly in property development. In 2001, she opened and ran the Sotheby's representative office in the Philippines.

She and her husband (banker and former Secretary of Energy and Secretary of Finance of the Philippines) Lito Camacho have been collecting art since 1981. Today, their collection has some of the most important works of one of the world's most popular artists, Yayoi Kusama. Their Gutai art collection is also well-known, having been started before Gutai was widely acclaimed in a Guggenheim New York retrospective. Both their Kusama and Gutai collections have been shown at the Ayala Museum. Their video art collection is considered to contain the largest private collection of digital video works of Japanese art collaborative, teamLab. Their collection also includes major works of American Abstract Expressionist, Alfonso Ossorio, and Filipino and Southeast Asian artworks. They regularly lend artworks to museums and art exhibitions around the world. She and Lito Camacho have 6 children, 2 of whom are artists- Bea, and Lorenzo. She now considers herself a full time art collector.